Waters HPLC Diagnóstico Y Corrección De Anomalías página 26

Peak Shape Problems Peak Shape Problems
Yes
Mechanical problem
— Tubing & fittings
— — Column voided Column voided
— Contaminated in-line
filter
— Injector problem
Chemical problem
— Sample solvent problem
All peaks affected?
No
Chemical problem
— Silanol activity
— — Column overload Column overload
— Co-elution
— Elution from previous
injection
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