MERCK ShutOut Guía Rápida

387458 R5
Teat sealant device for use in dry cows
Each syringe of ShutOut contains 4 g of a sterile, non-antibiotic, intramammary paste containing 2.6 g of bismuth
subnitrate.
For animal use only. Not for use in humans. Keep out of reach of children.
Read Entire Package Insert Carefully Before Using This Product
ShutOut is a sterile, antibiotic-free, smooth paste, presented in a ready- to-use syringe for intramammary infusion.
ShutOut is indicated as an aid in the prevention of new intramammary infections throughout the dry period by forming a
barrier in the teat canal. This results in a reduction in the incidence of clinical mastitis in the dry period.
It is recommended that ShutOut be used as part of a preventive integrated and holistic herd health approach to dry cow
management and mastitis control.
WITHDRAWAL INFORMATION: For use in dry cows only. Zero-day milk and meat withdrawal when used alone. If
ShutOut is administered following an antibiotic infusion, the withdrawal periods for meat and milk for the antibiotic must
be observed.
PRECAUTIONS: For animal use only. Not for use in humans. Keep out of reach of children.
ShutOut does not have any antimicrobial properties. Therefore, unintended introduction of mastitis-causing bacteria
needs to be avoided by following proper administration guidelines and sanitation.
To control this risk further, it is recommended to lower milk production towards dry off to prevent milk leakage during
and directly after administration of ShutOut, to aseptically administer the product into the teat using a predefined
protocol, to ensure a clean, dry, and comfortable environment during dry off and good environmental hygiene during and
directly after calving.
It is also good practice to observe dry cows regularly for signs of clinical mastitis. If a sealed quarter develops clinical
mastitis, the affected quarter should be stripped out manually before appropriate therapy is instituted.
In cows that may have subclinical mastitis, ShutOut may be used following administration of a suitable dry cow antibiotic
treatment to the infected quarter.
Please consult with your herd health veterinarian for therapy recommendations for cows with clinical and subclinical
mastitis.
To reduce the risk of contamination, do not immerse the syringe in water.
Use the syringe only once.
Do not administer any other intramammary product following administration of ShutOut
Special precautions for user:
If ShutOut gets on skin, wash with soap and warm water. If irritation persists, seek medical advice and show this label to
the doctor. If you know that you are allergic to bismuth salts, avoid using this product.
Wash hands after use.
Lactation:
If ShutOut is accidentally administered to a lactating cow, the product can be stripped out by hand.
STORAGE: ShutOut should be stored at room temperature 60°-85°F (~15°-30°C). In very cold temperatures, ShutOut
may become difficult to administer and should be warmed to room temperature. Individual syringes should not be
immersed in water. If there is a need to warm the syringes, the ShutOut bucket could be lowered into a 5-gallon bucket
filled with warm water.
INDICATIONS: ShutOut is indicated as an aid in the prevention of new intramammary infections of dairy cattle
throughout the dry period.
DOSAGE AND ADMINISTRATION: After last milking at dry-off, clean and disinfect the teats with the alcohol wipes
provided. Infuse the entire contents of one syringe of ShutOut into each quarter by inserting the nozzle into the teat and
applying gentle continuous pressure to the plunger until the paste is expressed. Do not massage the teat or udder
following infusion. If an antibiotic is infused into the teat, the teat should be re-wiped with the alcohol wipes provided
prior to infusion with ShutOut. A clean, disinfected and dry teat is essential, as ShutOut does not have any
antimicrobial properties.
ShutOut has the option to either use the short or the long tip of the syringe (Figure 1).
According to National Mastitis Council recommendations using the short tip is preferred because it has been shown to
result in fewer new intramammary infections.
Figure 1 – Short tip insertion
REMOVAL: Do not remove ShutOut by action of the milking machine. To reduce the potential for ShutOut accumulation
in milking machines, aggressively hand-strip ShutOut out of every quarter, 10 to 12 strips per quarter, before milking
fresh cows. Bucket-milk fresh cows for a minimum of three milkings, if possible.
CONTACT INFORMATION:
For technical assistance, call: 1-800-211-3573.
For customer service or to request a Safety Data Sheet (SDS), call: 1-800-521-5767.
Distributed by Intervet Inc. (d/b/a Merck Animal Health), Madison, NJ 07940.
Made in Germany.
Copyright © 2019 Intervet Inc., a subsidiary of Merck & Company Inc.
All rights reserved.
Rev. 10/19
References:
1. Boddie RL, Nickerson SC. Dry cow therapy: Effects of method of drug administration on occurrence of
intramammary Infection. J. Dairy Sci. 1986; 69:1, 253-257.
2. McDougall S. Management factors associated with the incidence of clinical mastitis over the non-lactation period
and bulk tank somatic cell count during the subsequent lactation. NZ Vet. J. 2003; 51:2, 63-72.