Infusion Rate vs Target Effect Site Concentration
Drug Concentration: 1.5 µg/ml
Volumetric accuracy: +0.8%
1200
1100
1000
900
800
700
600
500
400
300
200
100
0
0
5
10
15
20
Predicted Plasma vs Predicted Effect Site Concentration
Drug Concentration: 1.5 µg/ml
0.8
0.6
0.4
0.2
0.0
0
5
10
15
20
Profiles from TCI mode - BD 50ml Syringe
25
30
35
40
45
50
Time (mins)
25
30
35
40
45
50
Time (mins)
Target Effect
Predicted vs Ideal Effect Site Concentration
Drug Concentration: 1.5 µg/ml
Volumetric accuracy: +1.6%
0.5
0.5
0.4
0.4
0.3
0.3
0.2
0.2
0.1
0.1
0.0
0.0
0
5
55
60
0.8
0.6
0.4
0.2
0.0
55
60
1000DF00450 Issue 1
3/40
10
15
20
25
30
35
Time (mins)
0.5
0.4
0.3
0.2
0.1
0.0
40
45
50
55
60