Waters HPLC Diagnóstico Y Corrección De Anomalías página 12

Problem Gap in Column Outlet Problem Gap in Column Outlet
Fitting: Chromatogram and Data Fitting: Chromatogram and Data
0.06
0.04
0.02
0.00
0.04
0.02
0.00
0.06
0.04
0.02
0.00 0.00
0.00 0.50 1.00 1.50 2.00
Minutes
•System Benchmarking data
•
Acetone Retention Area
Average 0.323 52245
%RSD 0.69
Naphthalene Retention Area
Average 1.633 155515
%RSD 0.44
Acenaphthene Retention Area
Average 2.893 101332
%RSD 0.44
•No Gap
•Gap present
•No Gap
2.50 3.00 3.50 4.00
N=45
Plate
Tailing
Count
1.18 3144
Plate
Tailing
Count
1.13 11009
Plate
Tailing
Count
1.08 10436
0.010
0.005
0.000
0.010
0.000
0.010
0.005
0.000
0.50 1.00 1.50 2.00
•Benchmarking data + 9 injections
Acetone
Average
%RSD
Naphthalene Retention
Average
%RSD
Acenaphthene Retention
Average
%RSD
•USP Tailing: 1.12
•USP Tailing: 1.20
•USP Tailing: 1.12
2.50 3.00 3.50 4.00
Minutes
• (after fix)N=54
Retention Area Tailing
0.323 50599 1.18
0.67
Area Tailing
1.631 154565 1.12
0.45
Area Tailing
2.893 100707 1.08
0.44
©2007 Waters Corporation
Plate
Count
3159
Plate
Count
10751
Plate
Count
10247
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